Nexium, Prilosec and Prevacid linked to Chronic Kidney Disease
Many recent studies have linked Chronic Kidney Disease (CKD) to Nexium, Prilosec and Prevacid. This week, The Circulation Research Journal published results linking Nexium, Prilosec and Prevacid to accelerated blood vessel aging. Nexium, Prilosec and Prevacid accelerate blood vessel aging by causing a buildup of cellular garbage in the cellular linings. Accelerated blood vessel aging could result in an increased risk of cardiovascular and other complications.
Cellular Aging due to Nexium, Prilosec and Prevacid.
The study discovered that telomeres (a piece of chromosomes) were shortening when exposed to Proton Pump Inhibitors (PPIs), such as Nexium, Prilosec and Prevacid. Telomere shortening causes increased cellular aging. Endothelial cells exposed to Nexium in the study had a “fried egg” appearance, indicating cellular damage. The damaged cells were unable to divide properly or repair damaged blood vessels. Telomere shortening is also caused by free radical accumulation. Telomere shortening can result in chronic age-related conditions such as dementia, Alzheimer’s disease, cardiovascular disease and cancer. The study revealed that H2 blockers such as Zantac did not result in telomere shortening like Nexium, Prilosec and Prevacid.
Dr. John P. Cooke is chair of cardiovascular disease research at the Houston Methodist Research Institute and author of the recent study. In a recent interview Dr. Cooke expressed his confusion about how “the pharmaceutical industry didn’t run across this first.” Dr. Cooke continued by explaining that “this is something that should have been apparent a long time ago.” The side effects have been apparent to Dr. Cooke though, who has authored several studies on the risk of PPIs since 2013. Both of Dr. Cooke’s prior studies linked Nexium, Prilosec and Prevacid to cardiac complications, such as heart attacks. Even with all the evidence now available, the manufacturers still aren’t warning about the risk. Even more worrisome, is that the FDA has remained silent to date on the issue. Nexium, Prilosec and Prevacid are still obtainable over-the-counter.
Long-term use of Nexium, Prilosec and Prevacid Increases the Risk of Injury
Approximately 1 in 14 Americans use a Proton Pump Inhibitor to treat acid reflux or GERD. The FDA originally approved PPIs for up to four weeks at a time with a physicians prescription. However, once a drug has FDA approval, a physician can prescribe the medication however they see fit. Because the manufacturers of Nexium, Prilosec, and Prevacid failed to warn about the potential side effects, physicians didn’t abide by the four week limitation. Long-term use of PPIs greatly increases the risk of adverse events, especially chronic kidney disease.
Long-term use of Nexium, Prilsec, and Prevacid can also allude a physicians detection due to their over-the-counter availability. Of even greater concern is the fact that some patients are unaware that taking Nexium, Prilosec or Prevacid at the same time greatly increases the risk of an adverse event. Some patients even receive a generic proton pump inhibitor prescription and also buy Nexium over-the-counter. If you take over-the-counter Nexium, Prilosec or Prevacid, you should notify your doctor. These drugs are extremely dangerous when taken with other nephrotoxic drugs.
Nexium, Prilosec and Prevacid Lawsuit
Nexium, Prilosec, and Prevacid are among the most prescribed drugs in America. The manufacturer makes billions of dollars a year off these drugs by not warning of the side effects. Call us today at 1-800-701-3672 for a free Prilosec, Prevacid or Nexium Lawsuit evaluation. Our Nexium, Prilosec and Prevacid lawyers review all cases on an individual basis, free of charge.